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APC KAPS-Paper-1 Exam Syllabus Topics:

SectionWeightObjectives
Pharmaceutical Chemistry30%- Medicinal and Organic Chemistry
  • 1. Functional groups and chemical reactivity
    • 2. Drug stability and degradation pathways
      • 3. Drug classification and nomenclature
        • 4. Stereochemistry and isomerism
          • 5. Acid-base properties and pKa
            - Physical Pharmacy
            • 1. Physicochemical properties affecting drug action
              • 2. Chemical kinetics and shelf-life
                • 3. Partition coefficient and pH-partition theory
                  • 4. Solubility and dissolution
                    - Analytical Chemistry
                    • 1. Principles of drug analysis and identification
                      • 2. Quality control and purity assessment
                        Physiology and Pharmacology70%- Chemotherapy
                        • 1. Antiparasitic and antineoplastic drugs
                          • 2. Principles of antimicrobial resistance
                            • 3. Antibacterial, antiviral and antifungal agents
                              - Systemic Pharmacology
                              • 1. Central nervous system drugs
                                • 2. Cardiovascular and renal pharmacology
                                  • 3. Autonomic nervous system drugs
                                    • 4. Respiratory and gastrointestinal drugs
                                      • 5. Endocrine and metabolic pharmacology
                                        • 6. Anti-inflammatory, analgesic and immunomodulatory drugs
                                          - General Pharmacology
                                          • 1. Drug interactions and adverse effects
                                            • 2. Drug-protein binding and clearance
                                              • 3. Mechanisms of drug action and receptor theory
                                                • 4. Pharmacokinetics: absorption, distribution, metabolism, excretion
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